Ajattelin tämän artikkelin avulla toristaa Jahofvea:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196952/
"Loosening of associations is of particular relevance in Bleuler?s model of
schizophrenia because this symptom is intended to be primary?close to the
organic substrate of the disorder, and fundamental?always present over the
illness course. Thus, according to Bleuler, formal thought disorders would be
of paramount pathological and diagnostic importance. Cuesta and Peralta20 (in
this issue) address the specificity issue of formal thought disorders for
schizophrenia-spectrum disorders and major mood disorders, and more
specifically, they tested the hypothesis recently advanced in the Bulletin by
Lake21 that formal thought disorders are severe mood disorders. The authors
found that formal thought disorders are a multidimensional construct
comprising at least 5 domains: disorganized speech, verbosity, poverty of
speech, idiosyncratic thinking, and blocking. The disorganized speech factor
was the most relevant component of thought disorders and appeared to entail
the essential components of Bleuler?s loosening of associations. While
severity of formal thought disorder components significantly differed across
diagnosis, no one factor was specific to a given disorder. These findings do
not support neither Bleuler?s nor Lake?s hypotheses; in fact, they support the
consideration of formal thought disorders, and particularly disorganized
speech, as a relative unspecific syndrome within psychotic and major mood
disorders."